Testosterone cypionate
Testosterone Cypionate is the longest known form of testosterone to date. For sports purposes, men’s hormones have been used for a long time not only by men, but also by women. Thanks to the use of testosterone, there is a significant increase in the basic physiological parameters, which invariably affects the improvement of the results obtained during training.
Testosterone cypionate is the most popular and distributed in America, where the main production of the drug is concentrated. This steroid is produced by Balkan companies. The prolonged action of testosterone cypionate is due to the fact that the steroid is “seated” on the air, which allows it to remain in the fat depot for fifteen days.
The active substance is split off and enters the blood gradually. This “behavior” of the steroid minimizes the number of injections, which is quite convenient. If we consider enanthate and cypionate, these forms of testosterone may well replace each other, and are only released in the form of injections.
Course of cypionate administration
The optimal injection frequency is considered once every seven days. The prolonged action of cypionate allows to take a steroid and less often, but this pattern of injections does not provide an optimally high level of hormone concentration. Athletes trying to gain muscle mass, you need to focus on a daily dosage of 250-500 milligrams.
Solo courses Testosterone Cypionate allow you to get high results. They are great for beginning athletes, who do not need to take additional medications. It should be understood that an increase in the optimal injection rate of over 800 milligrams will not allow a more pronounced anabolic effect, but the chances of side effects will increase.
Combined courses are in many respects identical solo. The steroid is best combined with Nandrolone. The dosage of both drugs is about 200 milligrams per week. Blocking the estrogenic effect allows the use of Tamoxifen. It is used from the second week of the course at 10 milligrams every day and ends up being used fourteen days after the cypionate withdrawal. To normalize the secretion of their own testosterone, during the course take Proviron, replaced later by Tamoxifen.
Possible side effects
The steroid shows a high level of aromatization. Consequently, together with the increase in muscle mass, the concentration of estrogen also increases, which is the cause of the development of a disease such as gynecomastia, accompanied by compaction and swelling of the area around the nipples. To prevent the risks of manifesting gino, athletes take the blockers of aromatase and Nolvadex or Clomid, which are antiestrogens.
Side effects of cypionate administration are often due to high conversion of the hormone to the active form of dihydrotestosterone, are manifested by androgenic nature. In some cases, the athlete can raise blood pressure, observe hair growth on different parts of the body and on the face, or vice versa, baldness, acne, increased secretion of the sebaceous glands.
Testosterone Cypionate Reviews
The phenomenon of recoil after the abolition of cypionate can not be completely prevented, but the muscular mass gained, regardless of this, remains at a sufficiently high level. Reviews say that the side effects of the drug, with the exception of high fluid accumulation, almost never occur. Cypionate is a worthy competition enanthate and very effective.
Most professional bodybuilders combine cypionate with other drugs, but this approach is not recommended for beginners, as it increases the possibility of side effects. There are no leaders among the manufacturer of this testosterone, but preference should be given to American and European manufacturers, but they often belittle dosages and overestimate the cost. preparation h bodybuilding melatonin 10 mg bestellen bodybuilding and stretch marks
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Parabolan
Parabolan is a powerful steroid, a characteristic feature of which is the lack of aromatization. The basis of the drug is trenbolone hexahydrobenzyl carbonate. Initially, the remedy was used in animal husbandry. He was given to cattle in order to increase weight and increase appetite.
Trenbolone in its original form has a limited duration, therefore, esterified derivatives have become more widespread. Hexahydrobenzyl carbonate refers to one of them.
Injections of the ether require a prolonged action, when the substance enters the blood gradually. A good anabolic effect from Parabolan is obtained only with proper application. Disturbances in taking the drug are fraught with severe side effects.
What effect does Parabolan have?
The use of this steroid is facilitated by:
- Rapid increase in muscle mass, accounting for one course up to ten kilograms;
- Increase the strength of the athlete;
- Increased growth hormone production;
- Activation of the fat burning process;
- A sharp increase in sexual desire, rapidly reducing after the cancellation of the course, if not taken together Gonadotropin and Clomid;
- Double increase in insulin-like growth factor.
Temptol is a derivative of testosterone, but, unlike it, a drug based on this active substance has a tendency to androgen receptors five times stronger. This explains the high anabolic activity.
A similar ability to increase strength and muscle mass has only single steroids. The spread of Parabolan was greatly influenced by the fact that the effect of aromatase does not turn it into estrogens. Consequently, taking a steroid is not accompanied by fluid retention, and the probability of gynecomastia is reduced to zero.
How to take Parabolan
Without the use of Gonadotropin, a steroid is taken in a one and a half month course, that is, six weeks. Significant suppression of the production of androgenic testosterone in the body makes it expedient to include this drug as early as the second week after the start of the course. To drink Gonadotropin should be once a week for 500-1000 ml. Long-term PKT (post-course therapy) is two weeks. If the goal of the course is to increase muscle mass, the best result is achieved by the joint reception of Mriomobolan. It is administered once every seven days for 100-300 ml. Weekly dosage can be divided into two injections.
The solo Parabolana 100 allows you to achieve a significant increase in strength and weight. To enhance this effect, the steroid is combined with such drugs as Oxandrolone, Winstrol, Stanozolol, Methandienone, Primoblan, Bolderon and Oxymetholone, as well as esters of testosterone. The peculiarity of the drug is that it can be taken together with any anabolic, which is selected depending on a specific purpose. Absence of aromatization does not require the use of anti-estrogens after the cancellation of the course.
Possible side effects
Exceeding the dosages and duration of the course of taking this steroid almost always cause side effects. An athlete who neglects recommendations may experience an increase in blood pressure, insomnia, excessive aggressiveness, alopecia, acne, a decrease in libido and a sluggish erection.
An important condition is the admission to the course of Gonadotropin or Cabergoline. The toxic effect on the liver is moderate. Androgenic effects are manifested with rare exceptions, and estrogenic ones are absent. It is not recommended to combine the drug with Ephedrine and Clenbuterol.
Reviews about Parabolan
Negative feedback, as a rule, can be heard from beginning athletes. The newcomers mistakenly believe that the reddened urine is the result of a liver injury. This is a completely incorrect interpretation. Red it becomes because metabolites are excreted along with urine.
Experienced athletes, on the contrary, usually speak of a steroid positively. They note a rapid and weighty increase in weight, including among athletes with experience, an increase in libido, an increase in strength, a good fat burning effect. meal plan for bodybuilding peso muerto sumo cheapest bodybuilding supplements online bodybuilding grocery list buy anabolic steroids anastrozole bodybuilding dosage
Naposim
The action of Naposim, a drug produced by Vermoja, is based on methandienone, a substance that exhibits characteristic steroid properties. It increases the strength indicators, increases the growth of muscle mass, strengthens bone tissue, improves appetite, increases the synthesis of protein structures. The substance demonstrates a pronounced anti-catabolic effect.
The duration of methandienone activity is about five hours, and the detection period at the control is up to five weeks after the start of the competition. The drug is available in tablet form and has a toxic effect on the liver. Its androgenic activity is 50, and anabolic activity is 200 percent.
Both professional and novice athletes take a walk. The lack of sufficient experience can be an obstacle for the latter. Getting into the body, the tablets are quickly absorbed. For the course of admission you can dial up to ten kilograms, but not pure mass.
How to take Naposim
The average daily dosage recommended for admission to men is between 10 and 50 milligrams per day. The duration of the standard course varies between six and eight weeks. The maximum effect allows to achieve separation of the daily dose into two or three doses, which allows to prolong the activity of the active substance, which works for three to five hours.
Women are not recommended to take Naposim because of aromatization and androgenic activity, which provoke not the most favorable consequences. Some professional athletes use the drug, but in minimal dosages, that is, not more than 10 milligrams per day.
It should be borne in mind that not all women are sensitive to taking androgenic substances. For them, drugs of this nature do not carry any threat. In most cases, the use of NAPOSIM by girls can lead to the development of masculinization. Beginners, too, should not get carried away with the maximum dosages, and drink no more than 20 milligrams a day. Experienced athletes can take 50 mg per day in two divided doses.
Naposim take solo or integrated. On the course, it is combined with such drugs as Winstrol, Nandrolone and similar substances.
Reviews
Almost all athletes are happy with the course and gain a decent amount of muscle, but some athletes are rolled back. There are athletes who were difficult enough to adhere to the diet. These negative moments are not so common and not for all athletes, so the number of positive reviews is still prevailing.
Even at the first stages of reception, if the loads are sufficient, the mass increases by 2-3 kilograms. The main thing, it should be remembered that with increasing strength indicators, it is necessary to increase and load, taking scales heavier, performing more complex exercises. Otherwise, there will not be a large increase in mass. bodybuilding recipe book adrenolyn pre workout bodybuilding workout
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dianabol stack
Dianabol stack of biologically active compounds of Ginkgo dianabol stack extract (flavonoid glycosides, terpene lactones) may reduce vascular permeability, inhibit platelet aggregation. As a consequence, it improves microcirculation, supply of the brain and peripheral tissues of oxygen and glucose.
Indications
The drug is given at the elderly cerebrovascular disorders, accompanied by:
- disorders of attention and / or memory, violation of intellectual abilities,
- anxiety, fear,
- dizziness, tinnitus, sleep disturbances.
Appointed in cases of violation of the circulation of the lower limbs.Contraindications
: Hypersensitivity to the drug, reduced blood clotting, erosive gastritis, gastric ulcer and duodenal ulcer in the acute stage, children’s age (18 years).Dosing and Administration
The drug is given 1 capsule 3 times a day. The capsules should be swallowed with a little water. The course of treatment for at least 3 months. The first signs of improvement usually appear after 1 month. Repeat courses may, after consultation with the doctor.Side effects:
In rare cases, allergic reactions (skin rash), dyspepsia, headache, decreased blood clotting.Use of the drug during pregnancy and lactation
dianabol stack is not recommended during pregnancy and lactationOverdosing
Currently, the cases of drug overdose dianabol stack has not been reported.
dianabol dosage
Dianabol dosage is a selective, non-steroidal anti-androgen without having other types of endocrine activity. It is a racemic mixture of a non-steroidal antiandrogenic activity predominantly (R) -enantiomer. dianabol dosage binds to the androgen receptor and not activate gene expression, suppresses the stimulatory effect of androgens. The result is a regression of prostate tumors. In some patients receiving dianabol dosage cessation may lead to the development of the syndrome of “cancellation” anti-androgens. Dianabol dosage After intake of rapidly and completely absorbed from the gastrointestinal tract. Food intake does not affect absorption. (S) -enantiomer excreted faster (R) -enantiomer of the last half-life – about 7 days. With daily administration of dianabol dosage concentration of (R) -enantiomer in the plasma is increased by about 10 times because of the long half-life, which enables the drug once a day. The daily dose of dianabol dosage receiving 50 mg equilibrium concentration of the (R) enantiomer in the plasma of about 9 mg / ml. When administered 150 mg dianabol dosage daily equilibrium concentration of (R) enantiomer is approximately 22 mcg / mL. In the equilibrium state, about 99% of total circulating enantiomers of the active (R) -enantiomer. The connection to plasma proteins is high (for a racemic mixture of 96% for the (R) enantiomer 99.6%). The intensity and stereospecifically metabolized in the liver (by oxidation and glucuronic acid conjugates). The metabolites are not active, the kidneys and intestines in approximately equal proportions. In the pharmacokinetics (R) -enantiomer does not affect the age, renal impairment, mild to moderate hepatic dysfunction. There is evidence that patients with severely impaired liver function slows down the elimination of (R) enantiomer from plasma.
Indications
- Common prostate cancer in combination with an analogue of gonadotropin-releasing hormone (GnRH) or surgical castration.
- Locally common prostate cancer (TK-T4, any N, MO; T1-T2, N +, MO) as monotherapy or adjuvant therapy in combination with radiotherapy or radical prostatectomy.
- Locally advanced non-metastatic prostate cancer in cases where surgical castration or other medical intervention are not applicable or acceptable.
Contraindications
: Hypersensitivity to any component of the drug, simultaneous reception with terfenadine, astemizole, cisapride, lactase deficiency, lactose intolerance, glucose-galactose malabsorption (product contains lactose); childhood. Should not be administered to patients females. With caution Abnormal liver function.
Dosing and Administration
Inside.
Adult males (including the elderly..): When the prevalence of prostate cancer in combination with a GnRH analogue or surgical castration: 50 mg once daily. Treatment dianabol dosage should be started simultaneously with the start of reception of GnRH analogue or surgical castration. In locally advanced prostate cancer: 150 mg once a day. dianabol dosage should take a long time, for at least 2 years. If signs of progression of the disease taking the drug should be discontinued. Violations nochek function: Dosage adjustment is not required. Violations of the liver: in mild disturbance of function of the liver dose adjustment is required. In patients with moderate and severe hepatic impairment increased accumulation of dianabol dosage can be observed.
Side effects:
The pharmacological action of dianabol dosage may condition the following side effects:
- very common (> 10%): gynecomastia (may persist even after the cessation of therapy, particularly in the case of taking the drug for a long time), thoracic pain glands, “tides” of blood to the face;
- frequent (> 1% and <10%): diarrhea, nausea, transient increase in activity of “liver” transaminases, cholestasis and jaundice (described liver function changes are rarely rated as serious, they were transient in nature, completely disappeared or decreased with continued therapy or after cancellation drug), pruritus, asthenia; when use of the drug in a daily dose of 150 mg – alopecia or hair regrowth, decreased libido, sexual dysfunction, weight gain.
- rare (> 0.1% – <1%): hypersensitivity reactions, including angioedema and urticaria, interstitial lung disease; angina pectoris, prolongation of the interval QT, cardiac arrhythmias; when use of the drug in a daily dose of 150 mg – abdominal pain, depression, dyspepsia, hematuria.
- very rarely (> 0.01% – <0.1%): vomiting, dry skin (when using the drug in a daily dose of 150 mg of dry skin occurs often), liver failure (causal connection with taking dianabol dosage significantly is not installed) thrombocytopenia.
With simultaneous use of dianabol dosage and GnRH analogues can also experience the following adverse events with a frequency of> 1% (causal connection with taking the drug is not installed, some of the noted side effects occurred in elderly patients): Since the cardiovascular system: heart failure. From the digestive system: anorexia, dry mouth, dyspepsia, dysphagia, constipation, flatulence. From the nervous system: dizziness, headache, insomnia, somnolence. respiratory system: shortness of breath. From the urinary system: nocturia, urinary infections tract, dysuria, urinary retention, urinary frequency, polyuria, hydronephrosis. From the hematopoietic system: anemia, leukopenia. On the part of the skin and its appendages: alopecia, rash, sweating, hirsutism. From the laboratory parameters: hyperglycemia, increased activity of “liver” transaminases. Other: abdominal pain, chest pain, pelvic pain, back pain, decreased or increased body weight, edema, diabetes, fever.
Overdose
Cases of overdose have not been described in humans. There is no specific antidote. Treatment is symptomatic. Dialysis is not effective, since dianabol dosage is closely associated with proteins and excreted by the kidneys unchanged. Shown general supportive treatment and monitoring of vital body functions.
Interaction with other medicinal products
There are no data on the pharmacokinetic or pharmacodynamic interactions between dianabol dosage and GnRH analogues.
In in vitro studies have shown that (11) enantiomer of dianabol dosage inhibit CYP ZA4, to a lesser extent affecting the activity of CYP 2C9, 2C19 and 2D6. Potential to dianabol dosage for interaction with other drugs has been detected, but using dianabol dosage for 28 days to patients receiving midazolam, area under the curve “concentration-time» (AUC) midazolam is increased by 80%.
Incompatible with terfenadine, astemizole, cisapride.
caution must be exercised in the appointment of dianabol dosage together with cyclosporine or calcium channel blockers. You may need to decrease the dose of these drugs, particularly in the case or potentiation of side effects. After the start of the use or withdrawal of dianabol dosage is preferably carried out careful monitoring of cyclosporin plasma concentrations and the clinical condition of the patient.
The simultaneous use of dianabol dosage and drugs that inhibit microsomal oxidation of drugs, such as cimetidine or ketoconazole may increase dianabol dosage concentration in blood plasma and possibly to increase the incidence of adverse effects. It enhances the effect of coumarin anticoagulants, including warfarin (competition for protein binding).
Cautions
Given the possibility of slowing down excretion of dianabol dosage in patients with impaired hepatic function it is advisable to periodically assess liver function. Most of the changes of liver function occur in the first six months of treatment with dianabol dosage.
In the case of pronounced changes in hepatic function receiving the drug should be discontinued. In patients with disease progression on higher levels of prostate-specific antigen (PSA) should consider stopping treatment dianabol dosage.
In the appointment of dianabol dosage in patients receiving coumarin anticoagulants should regularly monitor the prothrombin time. Given the possibility of dianabol dosage inhibiting the activity of cytochrome P450 (CYP ZA4), caution should be exercised with concomitant administration of dianabol dosage with drugs primarily metabolized by the CYP ZA4.
Effects on ability to drive vehicles and management mechanisms
In the period of treatment must be careful when driving and occupation of other potentially hazardous activities that require high concentration and psychomotor speed reactions.
Product form
tablets covered with a foil cover, 50 mg and 150 mg. On 14 tablets in blisters of PVC film and aluminum foil. On 2 blisters with instruction on use are placed in a pile of cardboard.
Marking
on blister indicate the number of production licenses and a trademark of the manufacturer, in Russian indicate the name of the drug, dosage form, dosage, lot number, production date, shelf life «in bulk».
The label on the box and the boxes indicate the number of production licenses and trade the manufacturer’s mark on the Russian and English languages indicate the manufacturer, address, country, name of the drug, dosage form, dosage, name and content of active substances in one tablet, storage conditions, batch number, production date, shelf life, ” just for packaging “, the number of tablets in a blister, the number of blisters. When packing at CJSC “Skopinsky pharmaceutical plant” and CJSC “MAKIZ PHARMA”, Russian.
On the pack and the label for packaging in Russian indicate pre-acceptance of the manufacturer, his trademark, country, name of the company in charge of the packaging, its trade sign, address, phone / fax, the owner of the registration certificate, his trademark, address, phone / fax number, drug name, dosage form, dosage, name and content of active substances in one tablet, the number of tablets in the package, the storage conditions, “Apply for doctor’s prescription “,” Keep out of the reach of children “, the batch number, manufacturing date (corresponding to« in bulk »the date of manufacture of the drug), the expiry date. On the bundle further indicate dispensing conditions, method of application, registration number, pharmacotherapy-matic group, a bar code, “Contains lactose monohydrate.” In the group the package label indicates the number of additional packages.